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Molecular probes. --- Bioprobes --- Probes, Molecular --- Molecular biology --- Affinity labeling --- Technique

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Detectors --- Biosensors --- Chemical detectors --- Biosensing Techniques. --- Biosensors. --- Chemical detectors. --- Detectors. --- Sensors --- Chemical sensors --- Biodetectors --- Biological detectors --- Biological sensors --- Biomedical detectors --- Biomedical sensors --- Biosensing Technics --- Bioprobes --- Electrodes, Enzyme --- Bioprobe --- Biosensing Technic --- Biosensing Technique --- Biosensor --- Electrode, Enzyme --- Enzyme Electrode --- Enzyme Electrodes --- Technic, Biosensing --- Technics, Biosensing --- Technique, Biosensing --- Techniques, Biosensing --- Engineering instruments --- Physical instruments --- Chemical apparatus --- Medical instruments and apparatus --- Physiological apparatus --- Wearable Electronic Devices --- Microchemistry

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This new edition provides the most advanced research using bioprobes on the chemical control of 1) cell cycle and differentiation, 2) epigenetics, 3) apoptosis and autophagy, and 4) immune response. The “bioprobe”, first proposed in the first edition, has become an indispensable tool for chemical biology and has substantially assisted in the investigation of complex biochemical processes of cells. New areas of investigation such as stem cell research, epigenetic research, and autophagy research have rapidly advanced in the past 10 years. Including these new findings, this second edition supplies up-to-date information on the biochemical tools called bioprobes. Data on each bioprobe, such as chemical structure, origin, function, and references, are presented as one item in this volume. Readers will easily find useful information and will be able to determine the appropriate bioprobes to investigate cell functions. The information on bioprobes and their use in research makes this book a valuable source for researchers in diverse fields. Not only scientists in academia but also in the pharmaceutical industries will discover the most important information about small molecules useful for drug discovery.

Life sciences. --- Biotechnology. --- Organic chemistry. --- Biochemistry. --- Cell biology. --- Life Sciences. --- Cell Biology. --- Biochemistry, general. --- Organic Chemistry. --- Molecular probes. --- Bioprobes --- Probes, Molecular --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Organic chemistry --- Chemical engineering --- Genetic engineering --- Biosciences --- Sciences, Life --- Science --- Composition --- Molecular biology --- Affinity labeling --- Technique --- Cytology. --- Chemistry, Organic.

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Molecular imaging is a rapidly emerging field that translates many concepts developed for molecular biology and cellular imaging to the in vivo imaging of intact organisms. The technique allows the study of molecular biological events in their full context and will therefore become an indispensable tool for biomedical research and drug discovery and development.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities and the design of target reporter const

Molecular probes. --- Diagnostic imaging. --- Imaging systems in medicine. --- Medical imaging systems --- Medical instruments and apparatus --- Clinical imaging --- Imaging, Diagnostic --- Medical diagnostic imaging --- Medical imaging --- Noninvasive medical imaging --- Diagnosis, Noninvasive --- Imaging systems in medicine --- Bioprobes --- Probes, Molecular --- Molecular biology --- Affinity labeling --- Technique

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Reporter genes have been used for several decades to study regulation of gene expression in vivo. However, it was little more than a decade ago that a new class of reporter genes was developed for imaging molecular events within living subjects. By following the interactions of protein molecules, researchers can resolve the complex chemical pathways that living cells utilise. This book focuses on this group of imaging reporter genes, starting with detailed descriptions of all reporter genes from different imaging modalities, including optical, MRI, and radionuclide-based imaging. Key scientists in the field explain how to enhance reporter gene imaging utility through instrumentation and the various applications of this technology. This is the first comprehensive book on all aspects of reporter gene imaging, detailing what is known in the field and future goals for research. Investigators in biomedical sciences, physicians, and the biotechnology and pharmaceutical industries will benefit from topics covered.

Diagnostic imaging --- Molecular probes --- Reporter genes --- Molecular Imaging --- Genes, Reporter --- Reporter Genes --- Gene, Reporter --- Reporter Gene --- Promoter Regions, Genetic --- Genes --- Bioprobes --- Probes, Molecular --- Molecular biology --- Affinity labeling --- Clinical imaging --- Imaging, Diagnostic --- Medical diagnostic imaging --- Medical imaging --- Noninvasive medical imaging --- Diagnosis, Noninvasive --- Imaging systems in medicine --- methods --- Technique --- Reporter genes. --- Molecular probes. --- Diagnostic imaging.